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Post-doctoral position in neuroscience of aging

il y a 28 jours | Closing on Feb 20
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Université catholique de Louvain
Post-doctoral position in neuroscience of aging
Université catholique de Louvain
The Université catholique de Louvain (UCLouvain) is internationally recognized for research and teaching quality in many different fields of expertise.
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DÉTAILS DE L'OFFRE
Publié: il y a 28 jours
Date limite d'inscription: févr. 20
Localisation: Louvain-La-Neuve, Belgique
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Post-doctoral position in neuroscience of aging

We are looking for a highly motivated scientist to investigate the linking mechanisms between telomere erosion and the cellular pathways underlying neurodegenerative diseases.

Telomere shortening is a critical event in cell senescence, which is the major risk factor for the onset of age-related brain diseases. The general aim of our project is to study the impact of telomere shortening on brain cell physiology, and more precisely investigate its impact on cell senescence, mitochondrial activity and autophagic flux. We will further address the impact of telomere shortening on amyloid pathology that is characteristic of Alzheimer’s disease.

The position is available at UCLouvain (Brussels)- Institute of Neuroscience in collaboration with the De Duve Institute.

Primary responsibility of the candidate will include handling the transgenic mice strains combining telomere erosion and amyloid pathology, characterize the impairment of neuronal function in these models and investigate the molecular pathways linking telomere maintenance to amyloid pathology.

Hence, a thorough background in molecular biology and cellular models is necessary, as well as an expertise in handling of transgenic mice. Previous hands-on laboratory experience in neurobiology is required, and training in cell imaging would be highly beneficial. Candidates should have a PhD degree (or equivalent) in biology, biomedicine or related field.

The project will be conducted under the supervision of Prof. P. Kienlen-Campard (UCLouvain, Institute of Neuroscience) and Pr. Anabelle Decottignies (UCLouvain, De Duve Institute). The successful candidate will have the opportunity to work in both neurobiology and cancer biology laboratories, in an interdisciplinary -oriented environment. Good communication skills and good working knowledge of English are required.

A grant is available for 1 year with possible extension for a second year. Monthly net salary is of about 2200 euros, according to qualifications and experience.

CV and letters of motivation including 2 references should be addressed to pascal.kienlen-campard@uclouvain.be and anabelle.decottignies@uclouvain.be

REQUIREMENTS

Offer Requirements

  • REQUIRED LANGUAGES

    ENGLISH: Excellent

Skills/Qualifications

Thorough background in molecular biology and cellular models is necessary, as well as an expertise in handling of transgenic mice. Previous hands-on laboratory experience in neurobiology is required, and training in cell imaging would be highly beneficial. Candidates should have a PhD degree (or equivalent) in biology, biomedicine or related field.

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