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2 PhD Student Positions in Genetics of Vascular Diseases (MSCA-ETN V.A. Cure, ESR 1&2)

il y a 5 jours | Closing on May 01
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Université catholique de Louvain
2 PhD Student Positions in Genetics of Vascular Diseases (MSCA-ETN V.A. Cure, ESR 1&2)
Université catholique de Louvain
The Université catholique de Louvain (UCLouvain) is internationally recognized for research and teaching quality in many different fields of expertise.
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Publié: il y a 5 jours
Date limite d'inscription: mai 01
Localisation: Louvain-La-Neuve, Belgique
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2 PhD Student Positions in Genetics of Vascular Diseases (MSCA-ETN V.A. Cure, ESR 1&2)

The Human Genetics lab, part of the de Duve Institute in Brussels, aims to discover the genetic variations that drive human diseases. The lab uses NGS and bioinformatics to study patient samples and generates cellular and animal models to further dissect disease processes and test new therapies. It collaborates closely with clinicians and patients to provide viable and tangible knowledge-based improvements in health-care.

For the EU-MSCA-ETN project V.A. Cure, the lab invites applications for two Early Stage Researcher/PhD student positions entitled:

Identification of novel genes that cause Vascular Anomalies (ESR 1 and 2)

You will be part of a team of 14 ESRs working on the V.A. Cure project, which aims to uncover core mechanisms of initiation and maintenance of Vascular Anomalies with the final goal to establish novel therapeutic strategies. The project is funded in the frame of the EU MSCA-ITN programme.

Job description

You will work on a research project with the following objectives:

  • Identify a Vascular Anomaly-causative gene using Next Generation Sequencing (NGS)
  • Validate the effects of identified gene-mutations on function of the encoded protein in vitro
  • Identify molecular mechanisms, read-outs, and potential therapeutic targets in a cellular model of disease
  • Generate and characterize a zebrafish model of disease by gene knock-in (if gain of function)/ knock-down (if loss of function)
  • Identify genotype-phenotype correlations

You will also take part in the international training programme of the network and participate in various networking and outreach events.

Requirements

We are looking for a motivated student with a strong commitment to basic and/or translational research, who:

  • is eligible for MSCA-ETN funding, see www.vacure.eu
  • has an MSc degree in biology, biomedical sciences or related disciplines
  • is a team player with good communication skills

Appointment terms

The successful candidate will receive an attractive salary in accordance with MSCA regulations for Early Stage Researchers. The period of employment is 3 years. Starting date: June – October 2019.

How to apply

- Make sure you meet the qualifying requirements.

- Submit your application to info@vacure.eu by e-mail. Please send one pdf file containing:

•   A motivation letter describing your research career goals, skills and experience (cover letter)

•   Curriculum vitae

•   Grade transcripts and BSc/MSc diploma (in English or with a translation into English)

•   Two letters of recommendation or the contact information for at least 2 referees.

Deadline for submitting applications: 1 May 2019

More information

Please visit www.vacure.eu for more information on the project, the recruitment process and selection criteria. Contact for questions: Miikka.Vikkula@uclouvain.be

ADDITIONAL INFORMATION

Benefits

  • Be part of an international team of leading scientists in vascular biology.
  • Prestigious EU fellowship.
  • Develop multidisciplinary research skills.
  • Excellent training programme.
  • Establish a professional network in academia and industry.
  • Secondments and visits to partners in different countries.
  • Contribute to a better health care for people with severe rare diseases.

Eligibility criteria

To be eligible for a PhD student position, you must:

– not have resided or carried out your main activity (work, studies, etc.) in the country of the recruiting beneficiary for more than 12 months in the 3 years immediately before the recruitment date. Compulsory national service, short stays such as holidays, and time spent as part of a procedure for obtaining refugee status under the Geneva Convention are not taken into account.

– At the date of recruitment (=first day of employment), be in the first four years (full-time equivalent research experience) of your research career and not have been awarded a doctoral degree.

Selection process

The network consortium will preselect candidates for each position, based on the selection criteria mentioned below. Preselected candidates will be interviewed (face-to-face or via teleconferencing) by three consortium members. Final selection may involve an additional face-to-face interview. All interviews will be held in English. Before final selection you will be asked to send documents proving your eligibility.

Calendar:

Application deadline: 1 May 2019

Interviews: April – August 2019

Aimed start date: June – October 2019

All rejected candidates will receive a letter with a motivation of the rejection.

Selection criteria

– Academic results (grades, publications, other achievements)

– Proficiency in English

– Teamwork and communication skills

– Lab experience

– The impact of the proposed training on the researcher’s career

– Gender balance of the team

Additional comments

For other PhD positions in this project, visit www.vacure.eu.

REQUIREMENTS

Offer Requirements

  • REQUIRED LANGUAGES

    ENGLISH: Good

Skills/Qualifications

We are looking for a motivated student with a strong commitment to basic and/or translational research, who:

  • has a MSc degree in biology, biomedical sciences or related disciplines
  • is a team player with good communication skills
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